Chou TC, Talalay P
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Because ascorbate is abundant in most tissues, particularly in the brain, indirect information about the short-lived ROS formed in biological systems can be obtained from the quantitative evaluation of the level of ascorbyl radicals, considered terminal radicals of the cascade of radical reactions occurring in biological systems
However, it didnt cure schizophrenia.[ref] For COPD, a meta-analysis showed that lower doses (1200mg/day or less) for a duration of three months seemed to work best.[ref] A study in MS patients showed that 600 mg/2x/day did not significantly increase serum glutathione levels
As clinical use expands, indications broaden, and real-world experience accumulates, the volume of reported adverse events tends to increase gradually
